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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: The effect of the cholinergic anti-inflammatory pathway on collagen-induced arthritis involves the modulation of dendritic cell differentiation

Fig. 4

GTS-21 significantly downregulated CD11c expression in the synovium of collagen-induced arthritis (CIA) mice. a, b Immunohistochemical analysis was performed to detect CD11c expression in the knee joint tissues of mice (n = 8). CD11c+ cells (brown) were decreased significantly in the synovial tissues of the GTS-21 groups (a, 100×; b, 40×). c The integrated optical density (IOD) values of CD11c in synovial tissues were compared among the groups. Data are expressed as the mean ± standard deviation. *P <0.05 versus the control group; #P <0.05 versus the model group; &P <0.05 versus the vagotomy group

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Arthritis Research & Therapy

ISSN: 1478-6362

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