Table 1 Baseline demographic characteristics of the three groups of patients included in the analysis
Characteristic | Responders (n = 23) | Nonresponders (n = 43) | Placebo (n = 21) | P value |
|---|---|---|---|---|
Age, years, mean (SD) | 63.0 (14.1) | 53.5 (14.0) | 56.8 (10.5) | 0.043 |
Sex, n | 17 M, 6F | 37 M, 6F | 17 M, 4F | 0.48 |
Disease duration, years, mean (SD) | 17.0 (17.2) | 15.1 (9.8) | 14.9 (9.9) | 0.97 |
sUA, mg/dl, mean (SD) | 10.22 (1.76) | 10.50 (1.62) | 10.19 (1.82) | 0.68 |
Number of tophi assessed | 93 | 98 | 68 | NC |
Total tophus area, mm2, mean (SD) | 585.8 (795.0) | 661.5 (1298.7) | 674.4 (1011.6) | 0.32 |
Comorbidities, n | ||||
Hypertension | 16 | 30 | 17 | 0.60 |
Dyslipidemia | 14 | 17 | 10 | 0.25 |
Diabetes mellitus | 4 | 7 | 4 | 0.96 |
Coronary artery disease | 4 | 3 | 2 | 0.41 |