Factors related to health-related quality of life in ankylosing spondylitis, overall and stratified by sex

Table 3 Multivariable logistic regression analyses with MCS score below the median value as dependent variable

	All, n = 210 MCS < median MCS 48.0			Men, n = 121 MCS < median MCS 49.2			Women, n = 89 MCS < median MCS 46.0
Variables	OR	95% CI	P value	OR	95% CI	-value	OR	95% CI	P value
BMI, kg/m²	1.01	0.93 to 1.09	0.86
Civil state, single	3.04	1.34 to 6.91	0.008	2.24	0.76 to 6–61	0.14	13.21	2.13 to 81.96	0.006
Years in school, < 13 years				0.36	0.13 to 0.96	0.042
Ever smoker	1.26	0.61 to 2.58	0.53				1.35	0.38 to 4.76	0.64
VAS global fatigue, > median	6.36	3.06 to 13.19	< 0.001	7.73	2.63 to 22.76	< 0.001	17.29	3.82 to 78.23	< 0.001
Lateral spinal flexion, cm	1.02	0.95 to 1.09	0.64				0.94	0.81 to 1.10	0.44
BASFI, unit	1.18	0.93 to 1.50	0.16	1.41	0.99 to 2.00	0.057	1.07	0.73 to 1.57	0.72
ASDAS-CRP, ≥ 2.1	2.97	1.41 to 6.25	0.004	2.62	0.89 to 7.70	0.080	6.74	1.76 to 25.85	0.005
Log10mSASSS + 1, score							1.17	0.29 to 4.66	0.82
≥ 3 intervertebral bridges consecutively (only men)^a				0.17	0.044 to 0.65	0.01

Significant differences are in bold text. The independent variables were defined by having a univariate association with MCS (p-value ≤0.2) and not demonstrating collinearity. Due to some missing data, the models are based on overall 204 patients and in stratified analyses 117 men and 86 women
MCS mental component summary, OR odds ratio, CI confidence interval, BMI body mass index, VAS visual analogue scale, BASFI Bath Ankylosing Spondylitis Functional Index, ASDAS-CRP Ankylosing Spondylitis Disease Activity Score C-reactive protein, mSASSS Modified Stoke Ankylosing Spondylitis Spine Score, ^aCervical and/or lumbar spine

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