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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model

Fig. 5

KBP and naproxen effects on bone microstructure. μCT was performed to analyze structural effects of CIA and the treatments. Representative 3D reconstructions (a) with regions of interest (black boxes) and 2D contouring (b, c) indicate the area for three tibiotarsal (d, f) and metatarsal (e, g) analyses. The exact of bone volume to total volume (BV/TV, d, e) and trabecular thickness (Tb.Th, f, g) are reported. The data are presented as the means ± SEM of n = 10/group. Asterisk (*) indicates statistical comparisons to CIA control. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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