Fig. 1

Changes from baseline in skin sclerosis and pulmonary function over an 8-year period. Mean changes from baseline in the modified Rodnan skin score (mRSS; shown in a), percent predicted forced vital capacity (FVC; shown in b) and diffusing capacity of carbon monoxide (DLCO; shown in c) over an 8-year period. Results from the CD34-selected group and the unmanipulated group were compared. In the analysis of mRSS, patients with moderate-to-severe skin sclerosis (mRSS, ≥ 15) were included (CD34-selected, n = 9; unmanipulated, n = 6). Error bars represent standard deviation