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Table 4 Adverse events

From: CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan

  CD34-selected
(n = 11)
Unmanipulated
(n = 8)
p value
Grade 3 or 4 adverse event 6 (55) 2 (25) 0.35
Viral infections 9 (82) 2 (25) 0.02
CMV infection 7 (64) 1 (13) 0.06
Herpes zoster 6 (55) 0 (0) 0.02
Adenovirus haemorrhagic cystitis 2 (18) 0 (0) 0.49
Bacterial pneumonia 1 (9) 0 (0) 1.00
Sepsis 2 (18) 1 (13) 1.00
Cardiovascular 4 (36) 2 (25) 1.00
Pulmonary 1 (9) 1 (13) 1.00
Gastrointestinal haemorrhage 2 (18) 0 (0) 0.49
Hepatic 6 (55) 4 (50) 1.00
  1. Data are presented as n (%)