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Table 4 Adverse events

From: CD34-selected versus unmanipulated autologous haematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan

 

CD34-selected

(n = 11)

Unmanipulated

(n = 8)

p value

Grade 3 or 4 adverse event

6 (55)

2 (25)

0.35

Viral infections

9 (82)

2 (25)

0.02

CMV infection

7 (64)

1 (13)

0.06

Herpes zoster

6 (55)

0 (0)

0.02

Adenovirus haemorrhagic cystitis

2 (18)

0 (0)

0.49

Bacterial pneumonia

1 (9)

0 (0)

1.00

Sepsis

2 (18)

1 (13)

1.00

Cardiovascular

4 (36)

2 (25)

1.00

Pulmonary

1 (9)

1 (13)

1.00

Gastrointestinal haemorrhage

2 (18)

0 (0)

0.49

Hepatic

6 (55)

4 (50)

1.00

  1. Data are presented as n (%)