Fig. 1
From: Rheumatoid arthritis reprograms circadian output pathways
a Study design. Ten healthy and 10 RA patients were monitored for 1 week with an activity device, before a 24-h period in a clinical research facility. b PBMLs were isolated at 6 am and 6 pm; cells were stimulated with LPS/anti-CD3/28 mix for 2 h. c Mid sleep points were calculated for each subject. d Salivary cortisone concentration in healthy (n = 10) subjects and RA patients (n = 9). Graphs show the change in concentration over time. Individuals are tracked through time, and the group mean is plotted as a thick black line