Table 2 Laboratory parameters of 121 IgG4-RD patients with and without DS

HGB (g/L)

142 ± 14

130 ± 19

134 ± 18.3

0.016^#

WBC (10⁹/L)

7.27 ± 2.81

7.72 ± 2.47

7.5 ± 3.18

0.793

PLT (10⁹/L)

237 ± 50

259 ± 105

245.7 ± 171.3

0.747

Elevated Eos% (%)

33.3 (11/33)

17.9 (7/39)

43.5

0.042^#

ESR (mm/h), M (Q1–Q3)

13 (5–22)

36 (15–71)

31 (13–69)

0.002^#

Elevated ESR (%)

37.5 (12/32)

73.7 (28/38)

63.6 (28/44)

0.007^#

hsCRP (mg/L)

1.28 (0.55–2.18)

5.67 (2.03–17.7)

2.02 (0.94–7.9)

0.019^#

Elevated hsCRP (%)

12.5 (3/24)

57.1 (20/35)

37.5 (15/40)

0.002^#

IgG (g/L)

19.83 ± 7.34

18.06 ± 8.16

25.19 ± 11.7

0.002^#

Elevated IgG (%)

53.1 (17/32)

47.5 (19/40)

73.9

0.032^#

IgA (g/L)

1.84 ± 0.65

2.61 ± 1.33

1.92 ± 1.48

0.014^#

Elevated IgA (%)

0

12.5 (5/40)

2.2

–

IgM (g/L)

1.02 ± 1.12

1.13 ± 0.83

1.02 ± 2.56

0.944

Elevated IgM (%)

9.4 (3/32)

10 (4/40)

2 (4.3)

0.560

IgG1 (mg/L), M (Q1–Q3)

7530 (6500–10,028)

9250 (7950–11,100)

8580 (6770–10,100)

0.116

Elevated IgG1 (%)

5.9 (2/34)

17.9 (7/39)

13.3 (6/45)

0.300

IgG2 (mg/L), M (Q1–Q3)

5315 (4195–7488)

5700 (4170–7110)

5390 (3455–7020)

0.679

Elevated IgG2 (%)

38.2

38.5 (15/39)

31.1 (14/45)

0.727

IgG3 (mg/L), M (Q1–Q3)

474 (260–1123)

408 (247–932)

529 (276–884)

0.843

Elevated IgG3 (%)

26.5

20.5 (8/39)

15.6 (7/45)

0.490

IgG4 (mg/L), M (Q1–Q3)

8110 (4395–15,025)

3240 (1870–6455)

15,000 (8782–27,850)

< 0.001^#

Elevated IgG4 (n, %)

32 (94.1)

36 (87.8)

46 (100)

–

T-IgE (KU/L), M (Q1–Q3)

338 (76.6–555.3)

236 (102–686)

399 (169–1040.8)

0.447

Elevated IgE (%)

82.1 (23/28)

90.3 (28/31)

95 (38/40)

0.222

ALT (u/L)

31 ± 43.9

44.6 ± 89.9

39.8 ± 82.2

0.763

Cr (μmol/L)

67.3 ± 14.7

96.4 ± 89.8

78.3 ± 36.5

0.088

ANA+ (n, %)

4 (11.8)

3 (7.3)

8 (17.4)

0.360

RF+ (n, %)

8 (23.5)

5 (12.2)

3 (6.5)

0.083