Fig. 3

miR-191 inhibited apoptosis in RA-FLS. a RA-FLS were starved with 1% fetal serum for 24 h with or without overexpression of miR-191, followed by FACS analysis. b Bar graph showing the decreased apoptotic cell percentage after transfection with mimc-miR-191. c RA-FLS were starved with 1% fetal serum for 24 h with or without knockdown of miR-191, followed by FACS analysis. d Bar graph showing the increased apoptotic cell percentage after transfection with inhibitor-miR-191. e Transwell assays using RA-FLS cells after transfection with inhibitor-miR-191 for 24 h showed knockdown of miR-191 significantly suppressed the cell invasion of RA-FLS. f Quantitative analysis of e. All experiments were repeated three times. Data were presented as mean ± SEM (n = 3, *p < 0.05 by t test)