MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway

Table 3 Degeneration of rat caudal IVD at different time points

Time point	Non-degenerative IVD	Total degenerative IVD	Degenerative score	Degenerative rate	DHI (%)	RDHC
At the beginning	30	0	0	0	100 ± 0	1
The 2nd week	14	16	3.35 ± 0.30^*	53%^*	86.44 ± 3.00^*	0.75 ± 0.03^*
The 4th week	5	25	5.07 ± 0.41^*	83%^*	69.00 ± 2.37^*	0.70 ± 0.02^*

Note: n = 15
DHI disc height index, RDHC rate of disc height change, IVD intervertebral disc
^*p < 0.05 vs. the data obtained at the beginning; the comparison of data was conducted using a t-test

ISSN: 1478-6362