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Table 4 Supra-categories including the biological process gene ontology terms significantly overrepresented when comparing mesenchymal stem cells (MSCs) exposed to activated peripheral blood mononuclear cells (PBMCs) from rheumatoid arthritis (RA) patients vs. MSCs exposed to activated PBMCs from RA patients

From: RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients

Supra-category Number of categories in upregulated genes Number of categories in downregulated genes
Immune system-related 407 2
Signaling-related 89 0
Calcium metabolism-related 53 0
Development-related 50 18
Response to pathogens-related 45 0
Nucleic acids metabolism-related 18 0
Wound repair-related 12 0
Nitric oxide metabolism-related 6 0
Miscellanea 84 6