Fig. 11From: Increased peptidylarginine deiminases expression during the macrophage differentiation and participated inflammatory responsesA schematic diagram of this study showing that increased PADI2 and PADI4 expression during the differentiation of macrophages leads to IL-1β and TNF-α production and PAI-2 expression and citrullination. The citrullination of PAI-2 impaired its binding ability with PSMB1Back to article page