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Table 3 Regression analysis of correlation between mRSS and quantitative or categorical evaluation of organ involvement

From: Skin thickness score as a surrogate marker of organ involvements in systemic sclerosis: a retrospective observational study

 

Univariate analysis

Multivariate analysis

N

β (95% CI)

N

β (95% CI)

Lung involvement

 KL-6

177

5.14 (−3.38 to 13.7)

  

 SP-D

170

1.87* (0.27 to 3.47)

169

1.87* (0.09 to 3.65)

 %FVC

176

− 0.64*** (− 0.98 to − 0.30)

175

− 0.61** (− 0.98 to − 0.23)

 %DLco

171

− 0.67*** (− 1.00 to − 0.33)

170

− 0.53** (− 0.89 to − 0.16)

Heart involvement

 BNP

171

0.82 (− 0.02 to 1.66)

  

 LVEF

166

0.06 (− 0.05 to 0.17)

  

 E/e’

136

0.02 (− 0.04 to 0.09)

  

 RVSP

164

0.11 (− 0.02 to 0.25)

  

Renal involvement

 eGFR

177

0.44* (0.03 to 0.85)

176

0.11 (− 0.25 to 0.46)

Gastrointestinal involvement

 Los Angeles classification

161

0.02 (− 0.01 to 0.04)

  

Musculoskeletal involvement

 CK

177

1.99 (− 0.09 to 4.07)

  
  1. N number of the observation, β regression coefficient, CI confidence interval. Asterisk (*) indicates statistical significance in regression analysis.*P < 0.05; **P < 0.01; ***P < 0.001