Fig. 4

Skin and gastrointestinal lesions of patient 2. a Erythema nodosum in the bilateral lower extremities. b, c Pernio-like rash in the fingers. d, e Endoscopic findings at 29 years of age; d multiple ulcers in the gastric mucosa and e ulceration in the ileocecum. f, g CT findings at 29 and 33 years of age; f hepatosplenomegaly and g generalized lymphadenopathy. White arrows indicate swollen lymph nodes