Skip to main content

Table 2 Association between ISG score and haematological parameters

From: Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles

 

ISG negative (n = 101)

ISG positive (n = 63)

p value

Haemolytic anaemia

1/99 (1.01)

1/60 (1.67)

0.614

Haemoglobin (mg/dl)

13.4 (12.5, 13.9)

12.9 (11.6, 13.3)

0.004

Total WCC (109/l)

5.80 (4.55, 7.25)

4.95 (3.60, 5.80)

0.001

Lymphocyte count (109/l)

1.62 (1.27, 2.10)

1.31 (0.96, 1.75)

0.002

Neutrophil count (109/l)

3.39 (2.47, 4.51)

2.81 (1.99, 3.86)

0.020

Platelet count (109/l)

253 (221, 311)

249 (191, 286)

0.078

  1. Results are presented as the n(%) or median (IQR) as appropriate. Comparisons between groups were made using the Mann-Whitney U test (continuous variables) or Fisher’s exact test (categorical variables)
  2. ISG = interferon-stimulated gene, WCC = white cell count
  3. †As per the ACR SLE Classification criteria