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Table 1 Isothermal fluorescence values for CCL2, CCL7 and CXCL8 binding to HS and syndecan-3. Isothermal fluorescence values are expressed as dissociation constants (Kd) with standard error of the mean

From: Soluble syndecan-3 binds chemokines, reduces leukocyte migration in vitro and ameliorates disease severity in models of rheumatoid arthritis

  Heparan Sulfate (HS) Syndecan-3
Kd (nM) ± (SEM) Kd (nM) ± (SEM)
CCL2 508 32 94 20
CCL7 109 8 143 14
CXCL8 145 6 184 22