Number | Gene | Related protein* | Classification and function** |
---|---|---|---|
Non-SS vs. pSS | |||
1 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | T cell activation and proliferation, upregulation of NF-kappa-B signalling |
2 | CD44 | CD44 antigen | FOXP3 expression and regulatory T cell suppression, promotes tumour growth |
3 | B2MG | Beta-2-microglobulin | Antigen processing and presentation on MHC class I, innate immunity |
Controls vs. pSS | |||
1 | SLUR1 | Secreted Ly-6/uPAR-related protein 1 | Acetylcholine receptor activity, cell migration and proliferation |
2 | B2MG | Beta-2-microglobulin | Antigen processing and presentation on MHC class I, innate immunity |
3 | CLUS | Clusterin | Innate immunity, modulates NF-kappa-B activity and TNF production |