Table 1 Patient characteristics
Ice + cold CO2 (N = 47) | Ice (N = 31) | Ice (randomized phase, N = 16) | Cold CO2 (N = 16) | p value (ice versus CO2, randomized phase, N = 16 versus 16) | p value (ice versus CO2, N = 31 versus 16) | |
|---|---|---|---|---|---|---|
Diagnosis | RA (N = 13), SpA (N = 6), gout (N = 17), CPDD (N = 11) | RA (N = 10), SpA (N = 2), gout (N = 9), CPDD (N = 10) | RA (N = 3), SpA (N = 1), gout (N = 6), CPDD (N = 6) | RA (N = 3), SpA (N = 4), gout (N = 8), CPDD (N = 1) | 0.43 | 0.069 |
Age (years) | 60.1 [54.7–65.6] | 65.8 [59.6–71.9] | 65.9 [56.7–75.2] | 49.1 [39.9–58.4] | 0.007** | 0.002** |
Sex | M:25; F:22 | M:14; F:17 | M:11; F:5 | M:11; F:5 | 1 | 0.22 |
BMI (kg/m2) | 25.7 [24.3–27.1] (NA:1) | 26.1 [24.2–27.9] (NA:1) | 26.3 [23.4–29.3] (NA:1) | 24.9 [22.6–27.3] | 0.54 | 0.51 |
CRP (mg/L) | 110.5 [85.5–135.4] | 122.1 [87.9–156.2] | 131.6 [83.9–179.3] | 88 [54.5–121.5] | 0.19 | 0.4 |
First arthrocentesis volume (mL) | 15.7 [13.5–18] | 14.2 [12.4–16] | 15.4 [12.4–18.3] | 18.7 [13–24.4] | 0.4 | 0.13 |
Synovial leukocyte count (G/L) | 18.242 [11.158–25.326] (NA:9) | 17.277 [8.273–26.281] (NA:5) | 25.025 [6.702–43.348] (NA:4) | 20.333 [8.134–32.532] (NA:4) | 0.73 | 0.67 |