Fig. 12

Curcumin blocks the MSU-induced degradation of IκBα and NF-κB activation in the footpad tissue of mice with MSU-induced arthritis. a The total protein extracted from the footpad tissue was analyzed by immunoblotting for degradation of IκBα and NF-κB activation. b–h Densitometry measurements of protein analysis. The data represent the mean ± SEM of four mice per group. ^#Significantly different from vehicle (Veh) alone, P < 0.05. *Significantly different from MSU alone, P < 0.05