Fig. 6

Curcumin suppresses the expression of SOD2, Caspase-1 activation, and IL-1β maturation in the THP-1 cells. a Effects of curcumin on the MSU-stimulated expression levels of SOD2, p20 subunit of Caspase-1, and active p17 form of IL-1β; the expression levels were analyzed by western blot. b–d Densitometric analysis was used to quantify the level of SOD2, cleavage of caspase-1, and active p17 form of IL-1β. The data are expressed as mean ± SEM for three experiments. ^#Significantly different from absence both MSU and curcumin. *Significantly different from absence of curcumin, P < 0.05