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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: A multicenter randomized, double-blind, placebo-controlled pilot study to assess the efficacy and safety of riociguat in systemic sclerosis-associated digital ulcers

Fig. 3

Mean trend over time: change in net ulcer burden. Digital ulcer net burden is defined as the total number of “active” and indeterminate digital ulcers at an assessment. LS, least squares; SE, standard error; CI, confidence interval. Estimates are from an ANCOVA model with terms for the treatment group and baseline digital net ulcer burden. Modified intent-to-treat population is defined as all participants randomized, receiving at least one dose of treatment, and having at least one post-baseline efficacy assessment

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Arthritis Research & Therapy

ISSN: 1478-6362

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