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Table 5 Comparing the risks of opportunistic infection according to systemic rheumatic disease by Cox regression and competing risk regression models

From: Comparing the burdens of opportunistic infections among patients with systemic rheumatic diseases: a nationally representative cohort study

  Cox regression Competing risk regression
Crude HR Adjusted HR Crude sHR Adjusted sHR
Opportunistic infections
 SLE 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 PM/DM 1.38 (1.26–1.51) 1.18 (1.08–1.29) 1.22 (1.11–1.34) 1.17 (1.07–1.29)
 SSc 0.75 (0.67–0.85) 0.58 (0.51–0.65) 0.70 (0.62–0.78) 0.67 (0.59–0.75)
 RA 0.61 (1.26–1.51) 0.46 (0.44–0.48) 0.62 (0.59–0.65) 0.59 (0.57–0.62)
 pSS 0.57 (0.54–0.60) 0.42 (0.39–0.44) 0.58 (0.55–0.61) 0.56 (0.53–0.59)
Non-herpes zoster opportunistic infections
 SLE 1 (reference) 1 (reference) 1 (reference) 1 (reference)
 PM/DM 1.63 (1.41–1.89) 1.22 (1.05–1.42) 1.44 (1.24–1.68) 1.22 (1.05–1.43)
 SSc 0.83 (0.68–1.01) 0.55 (0.45–0.67) 0.77 (0.64–0.93) 0.65 (0.54–0.79)
 RA 0.50 (0.47–0.54) 0.33 (0.30–0.36) 0.51 (0.47–0.55) 0.45 (0.42–0.49)
 pSS 0.38 (0.34–0.42) 0.25 (0.22–0.28) 0.39 (0.34–0.43) 0.35 (0.31–0.39)
  1. HR hazard ratio, sHR subdistribution hazard ratio, SLE systemic lupus erythematosus, RA rheumatoid arthritis, pSS primary Sjögren’s syndrome, SSc systemic sclerosis, PM/DM polymyositis/dermatomyositis