Table 1 Univariate analysesa of predictive value of early MRI changes for later MRI and radiographic changes
Change from baseline to month 1 | Change from baseline to month 3 | ||||||
|---|---|---|---|---|---|---|---|
Change from baseline to month 12 | RAMRIS synovitis | RAMRIS osteitis | RAMRIS erosions | RAMRIS synovitis | RAMRIS osteitis | RAMRIS erosions | |
Total radiographic progressionb | Estimate (SE); p value | 0.044 (0.241); 0.856 | 0.007 (0.175); 0.971 | 1.431 (0.408); < 0.001 | 0.101 (0.188); 0.592 | − 0.087 (0.138); 0.533 | 0.748 (0.252); 0.004 |
Radiographic erosion progression | Estimate (SE); p value | 0.039 (0.118); 0.743 | 0.031 (0.085); 0.718 | 0.638 (0.201); 0.002 | 0.087 (0.091); 0.339 | − 0.013 (0.067); 0.853 | 0.455 (0.118); < 0.001 |
Radiographic JSN progression | Estimate (SE); p value | 0.010 (0.163); 0.951 | − 0.024 (0.118); 0.837 | 0.792 (0.284); 0.007 | 0.015 (0.127); 0.905 | − 0.074 (0.093); 0.434 | 0.295 (0.179); 0.104 |
RAMRIQ synovitisc | RAMRIQ osteitis | RAMRIQ erosions | RAMRIQ synovitisc | RAMRIQ osteitis | RAMRIQ erosions | ||
RAMRIS erosion progression | Estimate (SE); p value | 0.0002 (0.0001); 0.004 | 0.287 (0.085); 0.001 | – | 0.0001 (0.0000); 0.008 | 0.354 (0.089); < 0.001 | – |
Total radiographic progression b | Estimate (SE); p value | 0.0004 (0.0001); < 0.001 | 0.930 (0.154); < 0.001 | 1.552 (0.846); 0.072 | 0.0002 (0.0001); 0.008 | 1.099 (0.222); < 0.001 | − 0.498 (0.786); 0.529 |
Radiographic erosion progression | Estimate (SE); p value | 0.0001 (0.0000); 0.011 | 0.182 (0.092); 0.052 | 0.531 (0.417); 0.208 | 0.0001 (0.0000); 0.048 | 0.220 (0.123); 0.080 | − 0.231 (0.382); 0.548 |
Radiographic JSN progression | Estimate (SE); p value | 0.0003 (0.0001); < 0.001 | 0.748 (0.089); < 0.001 | 1.017 (0.572); 0.080 | 0.0002 (0.0001); 0.012 | 0.879 (0.138); < 0.001 | − 0.269 (0.533); 0.615 |