Skip to main content
Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture

Fig. 1

a H&E-stained section of bovine synovium harvested proximal to the patella. Tissue was cut to 25 ± 3 mg pieces containing a single intimal layer of synovium and no vasculature. Multiple images taken at × 10 magnification and stitched together to show the entire length of the tissue. b Experimental design. Cartilage tissue samples were cultured individually or in co-incubation with synovium tissue in serum-free media for 24 days. IL-1α was replenished every 2 days; IL-1Ra was replenished every 2 days in a continuous-dose condition while it was removed after day 2 in a single-dose condition

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us