Fig. 2

Comparison of fecal microbiota composition in patients with ankylosing spondylitis (AS) and healthy controls (HC). Fecal samples were analyzed by the GA-map™ Dysbiosis Test and evaluated using orthogonal partial least squares discriminant analysis (OPLS-DA). AS (n = 150) and HC (n = 17). a Score scatter plot from the OPLS-DA showing the separation between patients with AS (red circles) and HC (white circles). R2 defines the goodness of fit, and Q2 the goodness of prediction. b Loading column plot from the OPLS-DA. White columns represent bacteria in higher abundance in HC, and red columns represent bacteria in higher abundance in AS patients. All bacteria were included in the analysis, but the loading column plot shows only bacteria which abundance differed between the groups. Error bars represent 95% confidence interval. All analyzed bacteria are listed in Additional file 1: Table S1