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Table 4 Proportion of patients experiencing radiographic progression (Δ SHS ≥ 3) within each time interval against categories of diseases activity (time-integrated standardized DAS28 scores) in the same period

From: Radiographic progression can still occur in individual patients with low or moderate disease activity in the current treat-to-target paradigm: real-world data from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry

Time-integrated disease activity0–6-month progression6-month–1-year progression1-year–2-year progression2-year–3-year progression
NoYesNoYesNoYesNoYes
Low (DAS28 < 3.2)58 (77.3%)17 (22.7%)113 (83.1%)23 (16.9%)100 (77.5%)29 (22.5%)111 (84.1%)21 (15.9%)
Moderate (DAS28 3.2–5.1)79 (73.8%)28 (26.2%)20 (83.3%)4 (16.7%)15 (75.0%)5 (25.0%)8 (61.5%)5 (38.5%)
High (DAS28 > 5.1)7 (70.0%)3 (30.0%)2 (66.7%)1 (33.3%)0 (0.0%)1 (100%)1 (100%)0 (0.0%)
Total144 (75.0%)48 (25.0%)135 (82.8%)28 (17.2%)115 (76.7%)35 (23.3%)120 (82.2%)26 (17.8%)