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Fig. 13 | Arthritis Research & Therapy

Fig. 13

From: Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

Fig. 13

Effect of m-PGA on MIA-induced increase of mast cell density. Representative photomicrographs of toluidine blue-stained synovial sections. A quiescent mast cell densely packed with granules is visible (arrow) in the control group (a). Several degranulating mast cells were evident (arrows) in the synovium of MIA-injected rats (b). PGA (c) and m-PGA treatment (d) significantly decreased mast cell density (arrows) as confirmed by the statistical analysis (e). Results are expressed as means ± SEM (N = 10/group). ##p < 0.001 vs Control; *p < 0.05 vs vehicle; **p < 0.001 vs vehicle

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Arthritis Research & Therapy

ISSN: 1478-6362

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