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Fig. 8 | Arthritis Research & Therapy

Fig. 8

From: Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

Fig. 8

Effect of m-PGA on MIA-induced cartilage degeneration. Safranin O-fast green staining of articular cartilage in the knee joint of MIA-injected animals (b) showed a decrease in the proteoglycan content (red staining) as well as erosion and roughening of the articular cartilage and loss of the superficial zone compared to controls (a). PGA (c) and even more so m-PGA (d) treatment was able restore the histological appearance of the native cartilage (i.e., restored red staining)

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