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Table 3 Effect of MIA injection on plasma concentration of inflammatory, nociceptive, and matrix degradation markers in vehicle-treated animals

From: Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

 

IL-1

MMP-1

MMP-3

MMP-9

NGF

TNF-α

Control

N

10

10

10

10

10

10

Min

0.03

18

11

11

178

0.1

Max

0.06

26

20

21

191

0.5

Mean

0.04

22.7

15.6

15.9

185.3

0.30

SEM

0.00

1.08

1.06

1.19

1.65

0.04

Vehicle

N

10

10

10

10

10

10

Min

0.14

32

73

62

326

0.9

Max

0.18

47

92

77

388

1.4

Mean

0.16#

40.5#

83.7#

69.7#

363.3#

1.06#

SEM

0.01

1.64

1.84

1.37

5.44

0.05

  1. #p < 0.0001 vs Control
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Arthritis Research & Therapy

ISSN: 1478-6362

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