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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Increased levels of anti-dsDNA antibodies in immune complexes before treatment with belimumab associate with clinical response in patients with systemic lupus erythematosus

Fig. 1

Distribution and levels of autoantibodies in sera (a, e) and corresponding solubilized IC fractions (b, f) for patients (a, b) and 20 healthy controls (e, f). Levels are presented in arbitrary units (AU/mL) for all antibodies except for anti-dsDNA, which is presented in international units (IU/mL). The ratio between autoantibody levels in IC and conventional measurement in sera among the patients are presented as c percentage in IC as compared to sera and d as enrichment after correction for total IgG concentrations in IC and sera, respectively. Median levels are illustrated as horizontal solid lines and the corresponding values are stated below each panel. The horizontal dotted line in a and e shows the clinically recommended cutoff values for autoantibodies in serum (40 U/mL). a, e The prevalence (%) of specific autoantibodies in serum is presented above each antibody. Values below the measurement ranges are depicted as 0.1 for sera and 0.01 in IC. Ribo P ribosomal P

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Arthritis Research & Therapy

ISSN: 1478-6362

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