Fig. 4
Molecular characterization of dedifferentiated fat cells isolated from IAAT and SCAT. a–e Relative mRNA expression of SFRP2 (a), EN-1 (b), IL-6 (c), IL-8 (d), and Cox2 (e) by IFP- and SPFP-derived dedifferentiated adipocytes compared to the corresponding SCAT-derived DFATc from OA patients (n = 5–6). The relative mRNA expression was normalized to that of 18S RNA. f–h The secretion of IL-6 (f), IL-8 (g), and PGE2 (h) by DFATc isolated from IFPs, SPFPs, and SCATs (n = 5–6). Bars indicate the mean expression levels