Skip to main content

Advertisement

Table 3 Association of age group and sex with loss of tibial cartilage volume (%/year) over 10.7 years

From: Association of age, sex and BMI with the rate of change in tibial cartilage volume: a 10.7-year longitudinal cohort study

 Multivariable, β (95% CI)
MedialLateralTotal tibia
Combined (n = 428)
 Age 50–60 yearsRef.Ref.Ref.
 Age 60–70 years0.16 (− 0.01 to 0.33)0.07 (− 0.05 to 0.20)0.11 (0.00 to 0.22)
 Age 70–80 years0.38 (0.08 to 0.67)0.31 (0.08 to 0.53)0.35 (0.16 to 0.54)
p for trend0.0060.012< 0.001
Females (n = 211)
 Age 50–60 yearsRef.Ref.Ref.
 Age 60–70 years0.26 (0.01 to 0.51)0.11 (− 0.09 to 0.31)0.17 (− 0.01 to 0.34)
 Age 70–80 years0.29 (− 0.19 to 0.76)0.60 (0.22 to 0.98)0.47 (0.13 to 0.80)
p for trend0.0420.0070.004
Males (n = 217)
 Age 50–60 yearsRef.Ref.Ref.
 Age 60–70 years0.09 (− 0.14 to 0.32)0.02 (− 0.14 to 0.18)0.05 (− 0.08 to 0.19)
 Age 70–80 years0.41 (0.03 to 0.79)0.12 (− 0.15 to 0.39)0.27 (0.05 to 0.49)
p for trend0.0530.4490.035
Interaction with sex− 0.04 (− 0.29 to 0.21)− 0.17 (− 0.36 to 0.02)− 0.10 (− 0.26 to 0.07)
p for interaction0.7780.0840.241
  1. Model 1: adjusted for sex, BMI, radiographic osteoarthritis, history of knee surgery and knee injury, physical activity and site-specific tibial cartilage volume at baseline
  2. Model 2: adjusted for BMI, radiographic osteoarthritis, history of knee surgery and knee injury, physical activity and site-specific tibial cartilage volume at baseline
  3. Italicised data denotes statistically significant results