Skip to main content

Table 3 Association of age group and sex with loss of tibial cartilage volume (%/year) over 10.7 years

From: Association of age, sex and BMI with the rate of change in tibial cartilage volume: a 10.7-year longitudinal cohort study

 

Multivariable, β (95% CI)

Medial

Lateral

Total tibia

Combined (n = 428)†

 Age 50–60 years

Ref.

Ref.

Ref.

 Age 60–70 years

0.16 (− 0.01 to 0.33)

0.07 (− 0.05 to 0.20)

0.11 (0.00 to 0.22)

 Age 70–80 years

0.38 (0.08 to 0.67)

0.31 (0.08 to 0.53)

0.35 (0.16 to 0.54)

 p for trend

0.006

0.012

< 0.001

Females (n = 211)‡

 Age 50–60 years

Ref.

Ref.

Ref.

 Age 60–70 years

0.26 (0.01 to 0.51)

0.11 (− 0.09 to 0.31)

0.17 (− 0.01 to 0.34)

 Age 70–80 years

0.29 (− 0.19 to 0.76)

0.60 (0.22 to 0.98)

0.47 (0.13 to 0.80)

 p for trend

0.042

0.007

0.004

Males (n = 217)‡

 Age 50–60 years

Ref.

Ref.

Ref.

 Age 60–70 years

0.09 (− 0.14 to 0.32)

0.02 (− 0.14 to 0.18)

0.05 (− 0.08 to 0.19)

 Age 70–80 years

0.41 (0.03 to 0.79)

0.12 (− 0.15 to 0.39)

0.27 (0.05 to 0.49)

 p for trend

0.053

0.449

0.035

Interaction with sex

− 0.04 (− 0.29 to 0.21)

− 0.17 (− 0.36 to 0.02)

− 0.10 (− 0.26 to 0.07)

p for interaction

0.778

0.084

0.241

  1. †Model 1: adjusted for sex, BMI, radiographic osteoarthritis, history of knee surgery and knee injury, physical activity and site-specific tibial cartilage volume at baseline
  2. ‡Model 2: adjusted for BMI, radiographic osteoarthritis, history of knee surgery and knee injury, physical activity and site-specific tibial cartilage volume at baseline
  3. Italicised data denotes statistically significant results