Fig. 7
From: Unique primed status of microglia under the systemic autoimmune condition of lupus-prone mice
Analysis of the primed status of microglia from FcγRIIB−/−Yaa mice. a, b Confocal microscope images of microglia from FcγRIIB−/−Yaa mice revealed they had larger cell soma and hypertrophic processes (n = 3 for FcγRIIB−/−Yaa mice and controls). c Relative expressions of Tnf and Il6 genes after stimulation with a small amount of LPS. In b, data from three representative cells in three FcγRIIB−/−Yaa mice and three FcγRIIB+/+ mice were obtained, compared, and analyzed by Student’s t test. In c, sorted microglia from two to three mice per experiment were used for the experiments. Sum of three experiments was compared and analyzed by one-way ANOVA and post hoc Tukey’s multiple comparison test. *P < 0.05, **P < 0.01, and ***P < 0.01