Fig. 1

Clonal expansion and diversity of CD4⁺ T cell repertoire of healthy controls and IgG4-RD patients. The TCR repertoires of all the individuals were downsampled to the same number of reads (158,416 TCR sequences per sample). a Scatterplot showing the frequencies of all the TCR clones in each sample. Each dot represents one clone. b Frequency distribution of CD4⁺ T cell clones in healthy controls and IgG4-RD patients. Data were represented as mean and standard deviation (sd). c Shannon-Wiener index as quantification of TCR repertoire diversity of CD4⁺ T cells. Data were represented as mean and sd. Difference between groups was analyzed by Welch’s t test