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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: High-throughput sequencing of CD4+ T cell repertoire reveals disease-specific signatures in IgG4-related disease

Fig. 1

Clonal expansion and diversity of CD4+ T cell repertoire of healthy controls and IgG4-RD patients. The TCR repertoires of all the individuals were downsampled to the same number of reads (158,416 TCR sequences per sample). a Scatterplot showing the frequencies of all the TCR clones in each sample. Each dot represents one clone. b Frequency distribution of CD4+ T cell clones in healthy controls and IgG4-RD patients. Data were represented as mean and standard deviation (sd). c Shannon-Wiener index as quantification of TCR repertoire diversity of CD4+ T cells. Data were represented as mean and sd. Difference between groups was analyzed by Welch’s t test

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