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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis

Fig. 4

Retention of PlGF-2123-144-α-TNF at the injected paw. Cy7 labeled α-TNF or Cy7 labeled PlGF-2123-144-α-TNF was subcutaneously injected at the left hind footpad in the CAIA model. Top: Representative images of mice at 0.5, 1, 2, 3, 24, 48, 96, and 168 h after the injection. Bottom: changes in percent retention of the injected antibody at the left hind paw (n = 2, mean ± SE)

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