Table 4 Conditional analysis P values of HLA-B amino acid residues. Significance for association of lysine 70 (70K), asparagine 97 (97N), and histidine 114 (114H) is given in columns, either in unconditional analysis or conditioning on specific amino acid positions (where no letter is given after the HLA-B amino acid position number) or for specific amino acids (where a letter is given after the HLA-B amino acid position number), either individually or in combinations. NS = P > 0.05
70K | 97N | 114H | HLA-B*27 | |
|---|---|---|---|---|
Unconditional | 1.49 × 10−237 | 2.51 × 10−237 | 7.24 × 10−241 | 5.76 × 10−244 |
70 | – | 1.10 × 10−6 | 1.76 × 10−6 | 9.38 × 10−7 |
97 | 1.04 × 10−28 | – | 0.13 | 0.18 |
114 | 4.08 × 10−37 | 2.70 × 10−8 | – | 5.25 × 10−6 |
70 + 97 | – | – | 0.24 | 0.11 |
70 + 114 | – | 2.94 × 10−1 | – | 0.20 |
97 + 114 | 5.81 × 10−28 | – | – | 0.066 |
70 + 97 + 114 | – | – | – | 0.21 |
70K | – | 6.15 × 10−7 | 1.04 × 10−6 | 4.83 × 10−7 |
97N | 1.11 × 10−31 | – | 0.42 | 0.020 |
114H | 1.70 × 10−38 | 2.02 × 10−8 | – | 2.47 × 10−6 |
70K + 97N | – | – | 0.49 | 0.20 |
70K + 114H | – | 0.30 | – | 0.18 |
97N + 114H | 1.27 × 10−31 | – | – | 0.32 |
70K + 97N + 114H | – | – | – | 0.28 |