Fig. 5
From: Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis
Antibodies to new cartilage epitopes in BQ.Ncf1*mice with lpsCAIA and mCAIA. a Antibodies binding specifically to other unmodified epitopes, F4 (CII_T_F4_R-R), E10 (CII_T_E10_R), and U1 (CII_T_U1_R-R 501), in lpsCAIA (above) and mCAIA (below) were detected in Cab3- or anti-CII antibody-injected mice. b Antibodies binding specifically to citrullinated epitopes (CII_T_C1_CIT-CIT and C1_T_U1_CIT-CIT) in lpsCAIA (above) and mCAIA (below) were detected in Cab3- or anti-CII antibody-injected mice. The results show significance on days 9 and 95 in the Cab3 group, and on days 0 (naïve) and 95 in both the Cab3 and anti-CII groups. Data shown are mean ± SEM