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Table 1 Characteristics of the clinical and laboratory data of 78 patients with AAV

From: Serum interleukin-16 significantly correlates with the Vasculitis Damage Index in antineutrophil cytoplasmic antibody-associated vasculitis

Variables

Values

Demographic data

 Age (years)

62.0 (21.0)

 Male sex (N (%))

27 (34.6)

Variants (N(%))

 MPA

40 (51.3)

 GPA

21 (26.9)

 EGPA

17 (21.8)

AAV-specific indices

 BVAS

7.0 (11.0)

 FFS

1.0 (1.0)

 VDI

3.0 (2.0)

 SF-36 PCS score

48.0 (36.2)

 SF-36 MCS score

57.0 (34.5)

ANCA positivity (N(%))

 MPO-ANCA positivity

43 (55.1)

 PR3-ANCA positivity

7 (9.0)

 ANCA negativity

28 (35.9)

Clinical manifestations (N(%))

 General

27 (34.6)

 Cutaneous

9 (11.5)

 Mucous membrane and eye

5 (6.4)

 Ear, nose, and throat

36 (46.2)

 Pulmonary

50 (64.1)

 Cardiovascular

5 (6.4)

 Abdominal

0 (0)

 Renal

39 (50.0)

 Nervous system

17 (21.8)

Acute-phase reactants

 ESR (mm/h)

37.5 (44.0)

 CRP (mg/L)

2.6 (14.6)

IL-16 (pg/mL)

84.1 (198.7)

  1. Values are expressed as medians (interquartile ranges, IQR) or numbers (percentages)
  2. AAV ANCA-associated vasculitis, ANCA antineutrophil cytoplasmic antibody, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, EGPA eosinophilic granulomatosis with polyangiitis, BVAS Birmingham Vasculitis Activity Score, FFS Five-Factor Score, VDI Vasculitis Damage Index, SF-36 Short Form-36, P perinuclear, C cytoplasmic, MPO myeloperoxidase, PR-3 proteinase 3, AST aspartate aminotransferase, ALT alanine aminotransferase, ESR erythrocyte sedimentation rate, CRP C-reactive protein