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Table 1 Baseline characteristics according to cumulative average serum urate concentrations

From: Repeated measurements of serum urate and mortality: a prospective cohort study of 152,358 individuals over 8 years of follow-up

 

Q1

Q2

Q3

Q4

Q5

n

30,475

30,526

30,455

30,461

30,441

Men, n (%)

24,221 (79.5)

24,288 (79.6)

24,164 (79.3)

24,252 (79.6)

24,185 (79.4)

Age, years

49.5 ± 13.4

49.7 ± 13.7

48.9 ± 14.3

48.2 ± 15.0

47.3 ± 17.1

Average income, n (%)

 < 500¥/month

5084 (16.7)

6218 (20.4)

6105 (20.0)

5763 (18.9)

4982 (16.4)

 500–2999¥/month

20,643 (67.7)

19,717 (64.6)

19,595 (64.3)

19,361 (63.6)

18,582 (61.0)

 ≥ 3000¥/month

2507 (8.2)

2577 (8.4)

2678 (8.8)

2899 (9.5)

3250 (10.7)

Education, n (%)

 Illiteracy or elementary school

2648 (8.7)

2778 (9.1)

2645 (8.7)

2459 (8.1)

2295 (7.5)

 Middle school

25,198 (82.7)

24,710 (80.9)

24,034 (78.9)

23,076 (75.8)

21,493 (70.6)

 College/university

2116 (6.9)

2362 (7.7)

2887 (9.5)

3628 (11.9)

4387 (14.4)

Alcohol consumption status, n (%)

 Never

21,073 (69.1)

18,787 (61.5)

17,223 (56.6)

15,967 (52.4)

14,321 (47.0)

 Past

722 (2.4)

842 (2.8)

904 (3.0)

849 (2.8)

838 (2.8)

 Current

8225 (27.0)

10,322 (33.8)

11,559 (38.0)

12,471 (40.9)

13,210 (43.4)

Smoking status, n (%)

 Never

20,429 (67.0)

18,356 (60.1)

17,319 (56.9)

16,430 (53.9)

15,397 (50.6)

 Past

1070 (3.5)

1320 (4.3)

1449 (4.8)

1622 (5.3)

1637 (5.4)

 Current

8520 (28.0)

10,278 (33.7)

10,917 (35.8)

11,237 (36.9)

11,342 (37.3)

Sodium intake, n (%)

 ≥ 10 g/day

2616 (8.6)

3047 (10.0)

3191 (10.5)

3483 (11.4)

3547 (11.7)

 6–9 g/day

24,803 (81.4)

23,838 (78.1)

23,187 (76.1)

22,313 (73.3)

21,170 (69.5)

 < 6 g/day

2581 (8.5)

3029 (9.9)

3257 (10.7)

3437 (11.3)

3539 (11.6)

Physical activity, n (%)

 Never

3699 (12.1)

4203 (13.8)

4434 (14.6)

4554 (15.0)

4889 (16.1)

 1–2 times/week

22,908 (75.2)

21,601 (70.8)

20,663 (67.8)

20,044 (65.8)

18,776 (61.7)

 3+ times/week

3389 (11.1)

4111 (13.5)

4537 (14.9)

4635 (15.2)

4593 (15.1)

Use of antihypertensive agent, n (%)

2896 (9.5)

3736 (12.2)

4373 (14.4)

5219 (17.1)

6542 (21.5)

Use of lipid-lowering agent, n (%)

264 (0.87)

386 (1.26)

494 (1.62)

564 (1.85)

716 (2.35)

Use of hypoglycemic agent, n (%)

1562 (5.13)

1496 (4.90)

1266 (4.16)

1167 (3.83)

1114 (3.66)

Use of aspirin, n (%)

185 (0.61)

268 (0.88)

321 (1.05)

336 (1.10)

372 (1.22)

Father’s CVD history, n (%)

1371 (4.50)

1786 (5.85)

1985 (6.52)

2032 (6.67)

2042 (6.71)

Mother’s CVD history, n (%)

972 (3.19)

1197 (3.92)

1323 (4.34)

1316 (4.32)

1400 (4.60)

FBG1, mmol/L

5.70 ± 1.81

5.61 ± 1.53

5.55 ± 1.39

5.53 ± 1.31

5.53 ± 1.26

BMI1, kg/m2

24.1 ± 3.0

24.4 ± 3.1

24.8 ± 3.1

25.3 ± 3.2

26.0 ± 3.4

eGFR1, mL/min/1.73 m2

85.8 ± 18.0

87.3 ± 17.9

88.4 ± 17.9

88.9 ± 18.2

88.6 ± 20.4

LDL-c1, mmol/L

2.50 ± 0.64

2.52 ± 0.68

2.53 ± 0.72

2.53 ± 0.76

2.53 ± 0.79

TG1, mmol/L

1.40 ± 1.00

1.44 ± 1.00

1.56 ± 1.16

1.74 ± 1.30

2.11 ± 1.62

SBP1, mmHg

129 ± 18

129 ± 18

130 ± 18

130 ± 18

132 ± 19

DBP1, mmHg

82.8 ± 9.7

83.0 ± 9.6

83.4 ± 9.8

84.0 ± 10.0

85.0 ± 10.3

hs-CRP1,2, mg/L

0.87 (1.26)

1.01 (1.36)

1.15 (1.48)

1.30 (1.67)

1.57 (2.01)

  1. For continuous variables, mean ± SD
  2. For categorical variables, n (%)
  3. Abbreviations: UA serum urate, FBG fasting blood glucose, BMI body mass index, eGFR estimated glomerular filtration rate, LDL-c low-density lipoprotein cholesterol, TG triglycerides, SBP systolic blood pressure, DBP diastolic blood pressure, hs-CRP high sensitive C-reactive protein, CVD cardiovascular disease
  4. 1Cumulative average (see the “Methods” section)
  5. 2Present as median (interquartile range)