| Participants without gout (n = 5526) | Participants with gout (n = 187) | p value |
---|---|---|---|
HF hospitalization | |||
 Events/person-years | 223/50,163 | 20/1522 |  |
 Incidence rate (95% CI)* | 4.4 (3.9, 5.0) | 13.1 (7.4, 18.9) |  |
 Hazard ratio (95% CI) | |||
  Model 1 | 1 (reference) | 2.59 (1.63, 4.11) | < 0.001 |
  Model 2 | 1 (reference) | 2.59 (1.63, 4.11) | < 0.001 |
  Model 3 | 1 (reference) | 2.27 (1.41, 3.66) | 0.001 |
  Model 4 | 1 (reference) | 1.97 (1.22, 3.19) | 0.006 |
Coronary heart disease | |||
 Events/person-years | 453/48,904 | 24/1504 |  |
 Incidence rate (95% CI)* | 9.3 (8.4, 10.1) | 16.0 (9.6, 22.3) |  |
 Hazard ratio (95% CI) | |||
  Model 1 | 1 (reference) | 1.47 (0.97, 2.22) | 0.07 |
  Model 2 | 1 (reference) | 1.46 (0.97, 2.21) | 0.07 |
  Model 3 | 1 (reference) | 1.38 (0.91, 2.09) | 0.14 |
  Model 4 | 1 (reference) | 1.21 (0.79, 1.84) | 0.39 |
Stroke | |||
 Events/person-years | 398/48,702 | 14/1512 |  |
 Incidence rate (95% CI)* | 8.2 (7.4, 9.0) | 9.3 (4.4, 14.1) |  |
 Hazard ratio (95% CI) | |||
  Model 1 | 1 (reference) | 1.03 (0.60, 1.75) | 0.93 |
  Model 2 | 1 (reference) | 1.01 (0.59, 1.73) | 0.97 |
  Model 3 | 1 (reference) | 0.95 (0.56, 1.64) | 0.87 |
  Model 4 | 1 (reference) | 0.83 (0.48, 1.43) | 0.51 |
All-cause mortality | |||
 Events/person-years | 1858/50,142 | 85/1545 |  |
 Incidence rate (95% CI)* | 37.1 (35.4, 38.7) | 55.0 (43.3, 66.7) |  |
 Hazard ratio (95% CI) | |||
  Model 1 | 1 (reference) | 1.24 (1.00, 1.54) | 0.05 |
  Model 2 | 1 (reference) | 1.22 (0.98, 1.52) | 0.07 |
  Model 3 | 1 (reference) | 1.19 (0.95, 1.48) | 0.13 |
  Model 4 | 1 (reference) | 1.08 (0.86, 1.35) | 0.51 |