Synergistic activation of NF-κB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk

Table 1 Genotype distributions and SLE risk associations of TNFAIP3 and UBE2L3 SNPs

SLE systemic lupus erythematosus, SNP single-nucleotide polymorphism, OR odds ratio, CI confidence interval
^aMajor alleles are more frequent than minor alleles in controls. Shown in bold are the risk-associated alleles (r), which are more frequent in SLE cases than healthy controls. The nonrisk-associated alleles (n) are more frequent in controls than cases
^bUsing logistic regression with adjustment for age and gender of the participants

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