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Table 3 Multivariable adjusted risk ratios (RRa) for analgesic consumption according to clinical factors

From: Predictors of the use of analgesic drugs 1 year after joint replacement: a single-center analysis of 13,000 hip and knee replacements

 

Preoperative (0–3 months)

Postoperative (9–12 months)

Any analgesic**

Any analgesic**

Acetaminophen

NSAID

Opioid

Hip replacement

 Laterality:bilateral

1.1 (0.999–1.2)

0.82 (0.64–1.04)

0.34 (0.17–0.68)

1.02 (0.77–1.3)

0.67 (0.38–1.2)

 Harris Hip Score***

  Poor (< 70)

1

1

1

1

1

  Fair (70–80)

0.77 (0.63–0.94)

0.78 (0.54–1.1)

0.65 (0.29–1.4)

0.91 (0.61–1.3)

0.58 (0.22–1.6)

  Good or excellent (> 80)

0.49 (0.30–0.82)

0.60 (0.28–1.3)

1.36 (0.05–2.5)

0.72 (0.31–1.7)

Knee replacement

 Laterality:bilateral

1.1 (1.02–1.2)

0.86 (0.77–0.96)

0.77 (0.62–0.96)

0.91 (0.78–1.1)

0.56 (0.42–0.76)

 UKA (vs TKA)

0.72 (0.61–0.84)

0.83 (0.69–1.002)

0.45 (0.28–0.72)

0.99 (0.79–1.2)

0.52 (0.32–0.85)

 KSS Knee Score***

  Poor (< 60)

1

1

1

1

1

  Fair (60–70)

0.81 (0.71–0.92)

0.94 (0.82–1.1)

0.83 (0.62–1.1)

1.03 (0.86–1.2)

0.73 (0.50–1.05)

  Good or excellent (> 70)

0.78 (0.64–0.95)

0.88 (0.70–1.1)

0.81 (0.52–1.3)

0.94 (0.70–1.3)

0.82 (0.49–1.4)

 KSS Function Score***

  Poor (< 60)

1

1

1

1

1

  Fair (60–70)

0.94 (0.84–1.1)

1.03 (0.90–1.2)

1.3 (1.02–1.7)

0.90 (0.73–1.1)

0.91 (0.65–1.3)

  Good or excellent (> 70)

0.90 (0.82–0.99)

0.89 (0.80–1.00)

0.95 (0.75–1.2)

0.97 (0.83–1.1)

0.73 (0.55–0.97)

  1. RR (95% CI) adjusted with age (continuous), gender, Charlson Comorbidity Index, BMI (continuous), laterality (unilateral vs bilateral), and use of antidepressant 1 year before surgery
  2. **Acetaminophen, NSAID, opioid
  3. ***Preoperative HHS missing on 2138 (34.3%) patients and KSS Knee Score on 2617 (34.9%) patients and KSS Function Score on 2645 (35.3%) patients