Fig. 2

Percentage of 24-week responders among csDMARD/MTX-IR patients with/without interruption during the first 24 weeks. ACR20/50, 20%/50% improvement in American College of Rheumatology criteria; csDMARD, conventional synthetic disease-modifying antirheumatic drug; DAS28-hsCRP, Disease Activity Score based on a 28-joint count and high-sensitivity C-reactive protein; IR, inadequate responder; MTX, methotrexate