Table 2 Intra- and inter-day precision (CV%) and accuracy (bias%) at three QC levels
Intra-day (n = 5) | Inter-day (n = 20) | ||||||
|---|---|---|---|---|---|---|---|
QC level | Nominal concentration (ng/mL) | Mean concentration ± SD (ng/mL) | CV% | Bias% | Mean concentration ± SD (ng/mL) | CV% | Bias% |
LLOQ | 8.3 | 8.1 ± 0.3 | 3.2 | − 3.3 | 7.8 ± 0.4 | 4.9 | − 6.0 |
QCL | 25.0 | 23.3 ± 0.3 | 1.1 | − 6.9 | 22.6 ± 0.8 | 3.5 | − 9.5 |
QCH | 4556.3 | 4563.8 ± 205.0 | 4.5 | 0.2 | 4432.4 ± 157.5 | 3.6 | − 2.7 |