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Table 2 Intra- and inter-day precision (CV%) and accuracy (bias%) at three QC levels

From: Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS—evaluation of whole blood, plasma, and serum as sample matrices

  Intra-day (n = 5)Inter-day (n = 20)
QC levelNominal concentration (ng/mL)Mean concentration ± SD (ng/mL)CV%Bias%Mean concentration ± SD (ng/mL)CV%Bias%
LLOQ8.38.1 ± 0.33.2− 3.37.8 ± 0.44.9− 6.0
QCL25.023.3 ± 0.31.1− 6.922.6 ± 0.83.5− 9.5
QCH4556.34563.8 ± 205.04.50.24432.4 ± 157.53.6− 2.7