Fig. 2
From: Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice
Long bones of Mig-6-overexpressing mice are significantly shorter than those of control long bone during growth and aging. The lengths of the right humeri, tibiae, and femora were measured on microCT scans of mice at different ages using GE MicroView software. a 6-week-old male and female control and Mig-6-overexpressing mice. b Eleven-week-old male and female control and Mig-6-overexpressing mice. c Twelve-month-old male and female control and Mig-6-overexpressing mice. d Eighteen-month-old male and female control and Mig-6-overexpressing mice. (A1) Representative 3D isosurface reconstructions of 100 μm/voxel μCT scans. There were statistically significant differences between control and Mig-6over/over male and female groups. Individual data points presented with mean ± SEM (P < 0.05). Data analyzed by two-tailed Student t tests from 6 to 12 mice per group (age/gender)