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Table 1 Multivariable-adjusted correlates of healthcare utilization and mortality for serious infections in scleroderma

From: Serious infections in people with systemic sclerosis: a national US study

 

Hospital charges > median

Discharge to care facility

Length of hospital stay > 3 days

In-hospital mortality

Adjusted odds ratio (95% CI)

Age category

 < 50 years

Ref

Ref

Ref

Ref

 50 to < 65 years

1.06 (0.95, 1.19)

1.39 (1.19, 1.62)

1.10 (0.99, 1.22)

1.54 (1.24, 1.90)

 65–79 years

0.96 (0.85, 1.09)

2.01 (1.70, 2.38)

1.12 (0.99, 1.27)

2.08 (1.65, 2.63)

 ≥ 80 years

0.79 (0.68, 0.93)

4.17 (3.43, 5.08)

1.23 (1.05, 1.44)

3.23 (2.46, 4.24)

Sex

 Male

Ref

Ref

Ref

Ref

 Female

0.99 (0.89, 1.11)

0.98 (0.85, 1.11)

1.03 (0.93, 1.14)

0.93 (0.78, 1.10)

Race/ethnicity

 White

Ref

Ref

Ref

Ref

 Black

1.10 (0.96, 1.26)

1.13 (0.96, 1.33)

1.07 (0.94, 1.22)

1.15 (0.93, 1.43)

 Hispanic

1.20 (1.03, 1.39)

0.79 (0.65, 0.96)

0.95 (0.83, 1.09)

1.15 (0.92, 1.44)

 Other/missing

1.09 (0.98, 1.21)

0.98 (0.86, 1.12)

1.14 (1.03, 1.27)

1.20 (1.00, 1.44)

Deyo-Charlson score

 0

Not est

Not est

Not est

Not est

 1

Ref

Ref

Ref

Ref

 ≥ 2

1.54 (1.42, 1.68)

1.37 (1.23, 1.53)

1.44 (1.33, 1.57)

1.49 (1.28, 1.74)

Income category

 0–25th percentile

0.81 (0.71, 0.91)

0.94 (0.81, 1.09)

1.00 (0.89, 1.13)

0.82 (0.68, 1.00)

 25–50th percentile

0.83 (0.74, 0.93)

0.90 (0.78, 1.04)

1.01 (0.91, 1.13)

1.03 (0.86, 1.24)

 50–75th percentile

0.85 (0.76, 0.96)

0.96 (0.84, 1.10)

1.00 (0.90, 1.12)

0.95 (0.80, 1.13)

 75–100th percentile

Ref

Ref

Ref

Ref

Primary infection diagnosis

 Sepsis

Ref

Ref

Ref

Ref

 OI

0.87 (0.66, 1.15)

0.38 (0.27, 0.54)

1.48 (1.11, 1.97)

0.46 (0.30, 0.70)

 SSTI

0.42 (0.37, 0.47)

0.34 (0.29, 0.40)

0.65 (0.58, 0.73)

0.06 (0.04, 0.09)

 UTI

0.28 (0.23, 0.36)

0.34 (0.25, 0.46)

0.32 (0.26, 0.41)

0.02 (0.00, 0.11)

 Pneumonia

0.64 (0.58, 0.70)

0.38 (0.34, 0.43)

0.72 (0.66, 0.79)

0.29 (0.25, 0.34)

Insurance payer

 Medicare

1.16 (1.05, 1.30)

1.76 (1.52, 2.03)

1.21 (1.10, 1.35)

0.80 (0.67, 0.95)

 Medicaid

1.22 (1.05, 1.42)

1.48 (1.20, 1.82)

1.12 (0.97, 1.29)

0.90 (0.68, 1.18)

 Other

0.92 (0.69, 1.21)

1.29 (0.86, 1.93)

0.93 (0.71, 1.22)

1.46 (0.95, 2.25)

 Private

Ref

Ref

Ref

Ref

 Self

1.28 (0.93, 1.77)

0.79 (0.46, 1.38)

1.06 (0.78, 1.43)

1.08 (0.60, 1.94)

Hospital region

 Northeast

Ref

Ref

Ref

Ref

 Midwest

0.75 (0.66, 0.85)

1.00 (0.86, 1.16)

0.83 (0.73, 0.94)

0.66 (0.53, 0.81)

 South

0.92 (0.82, 1.03)

0.83 (0.72, 0.95)

0.95 (0.85, 1.07)

0.86 (0.71, 1.03)

 West

0.89 (0.78, 1.02)

0.85 (0.73, 1.00)

0.68 (0.60, 0.77)

0.83 (0.68, 1.01)

Hospital location/teaching

 Rural

Ref

Ref

Ref

Ref

 Urban non-teaching

2.57 (2.26, 2.92)

0.74 (0.63, 0.87)

1.38 (1.21, 1.57)

1.18 (0.93, 1.49)

 Urban teaching

2.25 (1.99, 2.54)

0.63 (0.54, 0.74)

1.31 (1.15, 1.48)

1.15 (0.91, 1.45)

Hospital bed size

 Small

Ref

Ref

Ref

Ref

 Medium

1.46 (1.29, 1.65)

1.05 (0.90, 1.23)

1.20 (1.06, 1.36)

1.23 (0.99, 1.55)

 Large

2.10 (1.89, 2.35)

1.01 (0.88, 1.16)

1.36 (1.22, 1.52)

1.35 (1.10, 1.66)

  1. CI confidence interval, Ref reference category; Odds ratio in bold font indicate that they were statistically significant with a p-value <0.05, i.e., the 95% confidence interval excludes 1.0