Fig. 6
From: Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease
GSK503 decreases autoantibody production in bm12 cGVHD. Lupus-like cGVHD was induced as in Fig. 1. GSK503 (125 mg/kg/day) was injected daily i.p [24]. starting 2 days before the induction of cGVHD. Anti-dsDNA and anti-chromatin autoantibody ELISAs were performed [14]. Five mice/group. Controls are non-cGVHD mice. Comparison between groups was assessed using the parametric Student t test. ***p < 0.001