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Table 6 Relationships between subchondral trabecular bone microarchitecture parameters and OA severity index for varus and valgus alignment group

From: Association between knee alignment, osteoarthritis disease severity, and subchondral trabecular bone microarchitecture in patients with knee osteoarthritis: a cross-sectional study

Parameters OARSI score K-L grade
M L M L
Varus (n = 60)
HKA 0.574 (0.338, 0.719)** − 0.337 (− 0.530, − 0.085)** 0.664 (0.494, 0.782)** − 0.088 (− 0.334, 0.147)
BV/TV 0.828 (0.722, 0.905)** 0.811 (0.729, 0.875)** 0.680 (0.492, 0.816)** 0.618 (0.455, 0.750)**
Tb.N 0.514 (0.306, 0.680)** 0.722 (0.598, 0.812)** 0.518 (0.301, 0.700)** 0.621 (0.474, 0.745)**
Tb.Th 0.700 (0.553, 0.807)** 0.688 (0.555, 0.789)** 0.565 (0.356, 0.720)** 0.443 (0.234, 0.623)**
Tb.Sp − 0.594 (− 0.725, − 0.410)** − 0.643 (− 0.775, − 0.471)** − 0.506 (− 0.697, − 0.281)** − 0.589 (− 0.726, − 0.431)**
BS/BV − 0.775 (− 0.846, − 0.672)** − 0.777 (− 0.857, − 0.668)** − 0.638 (− 0.783, − 0.445)** − 0.515 (− 0.685, − 0.309)**
Valgus (n = 11)
HKA 0.697 (0.409, 0.963)* − 0.718 (− 0.923, − 0.236)* 0.662 (0.177, 0.901)* − 0.504 (− 0.835, 0.054)
BV/TV 0.661 (0.184, 0.909)* 0.749 (0.388, 0.922)** 0.777 (0.407, 0.889)** 0.429 (− 0.131, 0.793)
Tb.N 0.417 (− 0.205, 0.808) 0.314 (− 0.189, 0.761) 0.299 (− 0.425, 0.843) − 0.143 (− 0.678, 0.370)
Tb.Th 0.680 (0.097, 0.917)* − 0.005 (− 0.716, 0.638) 0.299 (− 0.472, 0.848) − 0.048 (− 0.687, 0.682)
Tb.Sp − 0.397 (− 0.781, − 0.198) − 0.463 (− 0.797, − 0.007) − 0.359 (− 0.843, − 0.334) − 0.095 (− 0.461, 0.379)
BS/BV − 0.702 (− 0.927, − 0.143)* − 0.232 (− 0.698, 0.471) − 0.538 (− 0.878, − 0.121) 0.048 (− 0.676, 0.687)
  1. The indicated values are Pearson’s or Spearman’s coefficient and 95% confidence interval in brackets
  2. HKA hip-knee-ankle angle, BV/TV bone volume fraction, Tb.N trabecular number, Tb.Th trabecular thickness, Tb.Sp trabecular separation, BS/BV specific bone surface
  3. *P < 0.05, **P < 0.01