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Table 6 Relationships between subchondral trabecular bone microarchitecture parameters and OA severity index for varus and valgus alignment group

From: Association between knee alignment, osteoarthritis disease severity, and subchondral trabecular bone microarchitecture in patients with knee osteoarthritis: a cross-sectional study

Parameters

OARSI score

K-L grade

M

L

M

L

Varus (n = 60)

 HKA

0.574 (0.338, 0.719)**

− 0.337 (− 0.530, − 0.085)**

0.664 (0.494, 0.782)**

− 0.088 (− 0.334, 0.147)

 BV/TV

0.828 (0.722, 0.905)**

0.811 (0.729, 0.875)**

0.680 (0.492, 0.816)**

0.618 (0.455, 0.750)**

 Tb.N

0.514 (0.306, 0.680)**

0.722 (0.598, 0.812)**

0.518 (0.301, 0.700)**

0.621 (0.474, 0.745)**

 Tb.Th

0.700 (0.553, 0.807)**

0.688 (0.555, 0.789)**

0.565 (0.356, 0.720)**

0.443 (0.234, 0.623)**

 Tb.Sp

− 0.594 (− 0.725, − 0.410)**

− 0.643 (− 0.775, − 0.471)**

− 0.506 (− 0.697, − 0.281)**

− 0.589 (− 0.726, − 0.431)**

 BS/BV

− 0.775 (− 0.846, − 0.672)**

− 0.777 (− 0.857, − 0.668)**

− 0.638 (− 0.783, − 0.445)**

− 0.515 (− 0.685, − 0.309)**

Valgus (n = 11)

 HKA

0.697 (0.409, 0.963)*

− 0.718 (− 0.923, − 0.236)*

0.662 (0.177, 0.901)*

− 0.504 (− 0.835, 0.054)

 BV/TV

0.661 (0.184, 0.909)*

0.749 (0.388, 0.922)**

0.777 (0.407, 0.889)**

0.429 (− 0.131, 0.793)

 Tb.N

0.417 (− 0.205, 0.808)

0.314 (− 0.189, 0.761)

0.299 (− 0.425, 0.843)

− 0.143 (− 0.678, 0.370)

 Tb.Th

0.680 (0.097, 0.917)*

− 0.005 (− 0.716, 0.638)

0.299 (− 0.472, 0.848)

− 0.048 (− 0.687, 0.682)

 Tb.Sp

− 0.397 (− 0.781, − 0.198)

− 0.463 (− 0.797, − 0.007)

− 0.359 (− 0.843, − 0.334)

− 0.095 (− 0.461, 0.379)

 BS/BV

− 0.702 (− 0.927, − 0.143)*

− 0.232 (− 0.698, 0.471)

− 0.538 (− 0.878, − 0.121)

0.048 (− 0.676, 0.687)

  1. The indicated values are Pearson’s or Spearman’s coefficient and 95% confidence interval in brackets
  2. HKA hip-knee-ankle angle, BV/TV bone volume fraction, Tb.N trabecular number, Tb.Th trabecular thickness, Tb.Sp trabecular separation, BS/BV specific bone surface
  3. *P < 0.05, **P < 0.01