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Table 1 SLE patients’ characteristics of both observatory and replication datasets

From: Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population

Patients’ characteristics Clinical cases
Observatory cohort n = 455a Replication cohort n = 371a
  n (%) n (%)
Age of onset (mean ± SD) 30.38 ± 13.68 30.39 ± 11.43
Sex
 Female 425 (93.41%)b 337 (90.84%)c
 Male 26 (5.71%)b 27 (7.28%)c
Clinical aspects
 Hemologic disorders 243 (53.41%)b 136 (36.66%)c
 Neurological disorders 62 (13.63%)b 33 (8.89%)c
 Ulcer 115 (25.27%)b 52 (14.02%)c
 Discoid rash 161 (35.38%)b 49 (13.21%)c
 Malar rash 142 (31.21%)b 82 (22%)c
 Arthritis 133 (29.23%)b 148 (39.89%)c
 Renal disorders 284 (62.42%)b 149 (40.16%)c
 ANA 350 (76.92%)b 214 (57.68%)c
  1. aThe sample number after quality control processes
  2. bThe percentages of unknown clinical data (n/a) in the observatory dataset are listed here. Sex = 0.88%, hematologic disorder = 1.76%, neurological disorder = 2.20%, ulcer = 4.18%, discoid rash = 3.96%, malar rash = 5.71%, arthritis = 4.18%, renal disorders = 1.76%, and ANA = 9.89%
  3. cThe percentages of unknown clinical data (n/a) in the replication dataset are listed here. Sex = 0.00%, hematologic disorder = 36.93%, neurological disorder = 37.2%, ulcer = 37.4%, discoid rash = 37.2%, malar rash = 37.47%, arthritis = 37.2%, renal disorders = 37.74%, and ANA = 36.93%