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Table 1 SLE patients’ characteristics of both observatory and replication datasets

From: Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population

Patients’ characteristics

Clinical cases

Observatory cohort n = 455a

Replication cohort n = 371a

 

n

(%)

n

(%)

Age of onset (mean ± SD)

30.38

± 13.68

30.39

± 11.43

Sex

 Female

425

(93.41%)b

337

(90.84%)c

 Male

26

(5.71%)b

27

(7.28%)c

Clinical aspects

 Hemologic disorders

243

(53.41%)b

136

(36.66%)c

 Neurological disorders

62

(13.63%)b

33

(8.89%)c

 Ulcer

115

(25.27%)b

52

(14.02%)c

 Discoid rash

161

(35.38%)b

49

(13.21%)c

 Malar rash

142

(31.21%)b

82

(22%)c

 Arthritis

133

(29.23%)b

148

(39.89%)c

 Renal disorders

284

(62.42%)b

149

(40.16%)c

 ANA

350

(76.92%)b

214

(57.68%)c

  1. aThe sample number after quality control processes
  2. bThe percentages of unknown clinical data (n/a) in the observatory dataset are listed here. Sex = 0.88%, hematologic disorder = 1.76%, neurological disorder = 2.20%, ulcer = 4.18%, discoid rash = 3.96%, malar rash = 5.71%, arthritis = 4.18%, renal disorders = 1.76%, and ANA = 9.89%
  3. cThe percentages of unknown clinical data (n/a) in the replication dataset are listed here. Sex = 0.00%, hematologic disorder = 36.93%, neurological disorder = 37.2%, ulcer = 37.4%, discoid rash = 37.2%, malar rash = 37.47%, arthritis = 37.2%, renal disorders = 37.74%, and ANA = 36.93%
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Arthritis Research & Therapy

ISSN: 1478-6362

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