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Table 1 Characteristics of all patients

From: AST/ALT ratio as a predictor of mortality and exacerbations of PM/DM-ILD in 1 year—a retrospective cohort study with 522 cases

Characteristic All (n = 522) Male (n = 167) Female (n = 355) p value
Age, years   49.54 (12.06)* 50.09 (11.25)* 0.619
Diagnosis     0.085
 DM 360 (69) 126 (75.4) 234 (65.9)  
 CADM 47 (9) 11 (6.6) 36 (10.1)  
 PM 115 (22) 30 (18) 85 (23.9)  
OLS   9 (5.4) 41 (11.5) 0.026
Comorbidities
 Diabetes mellitus 36 (6.9) 13 (7.8) 23 (6.5) 0.583
 Hypertension 54 (10.3) 19 (11.4) 35 (9.9) 0.595
 Chronic hepatitis B 24 (4.6) 9 (5.4) 15 (4.2) 0.554
MDA5+ 70 (13.4) 25 (15) 45 (12.7) 0.473
HB   130 (120–146) 121 (109–131) < 0.001
PLT   194 (143–254) 195 (148–262) 0.508
EO%   0.6 (0.1–2.6) 0.7 (0.2–2.4) 0.653
NLR   4.52 (3.09–7.82) 4.25 (2.99–6.84) 0.323
TBIL   9 (6.8–12.3) 8.4 (6.5–11) 0.042
DBIL   3.3 (2.5–4.6) 3 (2.4–3.9) 0.005
IBIL   5.2 (4.1–7.8) 5.5 (4–6.9) 0.441
TP   65.2 (59.8–70.5) 65.9 (61.4–71.1) 0.147
ALB   34.9 (31.3–38.4) 34.3 (30.7–37.9) 0.272
GLB   29.8 (25.4–33.7) 31.7 (27.6–35.9) 0.002
AST/ALT   1.12 (0.77–1.56) 1.30 (1–1.82) < 0.001
UA/CREA   5.3 (3.93–6.51) 5.35 (4.29–7.05) 0.062
TG   1.82 (1.35–2.51) 1.97 (1.45–2.79) 0.016
LDL   2.46 (1.81–3.05) 2.29 (1.68–3) 0.221
CK   110 (52–703) 136 (42–1156) 0.943
Readmission within 1 year   36 (21.6) 67 (18.9) 0.472
Need for MV within 1 year   15 (9) 28 (7.9) 0.671
Deaths within 1 year   21 (12.6) 43 (12.1) 0.881
  1. Data are presented as n, n (%) for categorical variables and median (interquartile range) for continuous variables
  2. *: mean (standard deviation)
  3. Bold indicates statistical significance
  4. DM dermatomyosis, CADM clinically asymptomatic dermatomyosis, PM polymyosis, OLS overlap syndrome, MDA5 anti-melanoma differentiation-associated gene 5, HB hemoglobin, PLT platelet count, WBC white blood cell count, EO% percentage of eosinophils, NLR neutrophil/lymphocyte ratio, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, TP total protein, ALB albumin, GLB globin, UA uric acid, CREA creatinine, TG triglycerides, LDL low-density lipoprotein, CK creatine kinase, MV mechanical ventilation