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Table 1 Characteristics of all patients

From: AST/ALT ratio as a predictor of mortality and exacerbations of PM/DM-ILD in 1 year—a retrospective cohort study with 522 cases

Characteristic

All (n = 522)

Male (n = 167)

Female (n = 355)

p value

Age, years

 

49.54 (12.06)*

50.09 (11.25)*

0.619

Diagnosis

   

0.085

 DM

360 (69)

126 (75.4)

234 (65.9)

 

 CADM

47 (9)

11 (6.6)

36 (10.1)

 

 PM

115 (22)

30 (18)

85 (23.9)

 

OLS

 

9 (5.4)

41 (11.5)

0.026

Comorbidities

 Diabetes mellitus

36 (6.9)

13 (7.8)

23 (6.5)

0.583

 Hypertension

54 (10.3)

19 (11.4)

35 (9.9)

0.595

 Chronic hepatitis B

24 (4.6)

9 (5.4)

15 (4.2)

0.554

MDA5+

70 (13.4)

25 (15)

45 (12.7)

0.473

HB

 

130 (120–146)

121 (109–131)

< 0.001

PLT

 

194 (143–254)

195 (148–262)

0.508

EO%

 

0.6 (0.1–2.6)

0.7 (0.2–2.4)

0.653

NLR

 

4.52 (3.09–7.82)

4.25 (2.99–6.84)

0.323

TBIL

 

9 (6.8–12.3)

8.4 (6.5–11)

0.042

DBIL

 

3.3 (2.5–4.6)

3 (2.4–3.9)

0.005

IBIL

 

5.2 (4.1–7.8)

5.5 (4–6.9)

0.441

TP

 

65.2 (59.8–70.5)

65.9 (61.4–71.1)

0.147

ALB

 

34.9 (31.3–38.4)

34.3 (30.7–37.9)

0.272

GLB

 

29.8 (25.4–33.7)

31.7 (27.6–35.9)

0.002

AST/ALT

 

1.12 (0.77–1.56)

1.30 (1–1.82)

< 0.001

UA/CREA

 

5.3 (3.93–6.51)

5.35 (4.29–7.05)

0.062

TG

 

1.82 (1.35–2.51)

1.97 (1.45–2.79)

0.016

LDL

 

2.46 (1.81–3.05)

2.29 (1.68–3)

0.221

CK

 

110 (52–703)

136 (42–1156)

0.943

Readmission within 1 year

 

36 (21.6)

67 (18.9)

0.472

Need for MV within 1 year

 

15 (9)

28 (7.9)

0.671

Deaths within 1 year

 

21 (12.6)

43 (12.1)

0.881

  1. Data are presented as n, n (%) for categorical variables and median (interquartile range) for continuous variables
  2. *: mean (standard deviation)
  3. Bold indicates statistical significance
  4. DM dermatomyosis, CADM clinically asymptomatic dermatomyosis, PM polymyosis, OLS overlap syndrome, MDA5 anti-melanoma differentiation-associated gene 5, HB hemoglobin, PLT platelet count, WBC white blood cell count, EO% percentage of eosinophils, NLR neutrophil/lymphocyte ratio, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, TP total protein, ALB albumin, GLB globin, UA uric acid, CREA creatinine, TG triglycerides, LDL low-density lipoprotein, CK creatine kinase, MV mechanical ventilation